Endocrine Abstracts

Background: Chemerin is a recently identified adipocyte-secreted signalling molecule (adipokine) that regulates adipocyte differentiation, metabolism, and inflammation through activation of the cognate receptor Chemokine-Like Receptor 1 (CMKLR1). Circulating chemerin levels are increased in obese patients as well as in patients with inflammatory bowel disease (IBD) such as Crohn’s disease and ulcerative colitis. Increased white adipose tissue mass (WAT) and resultant chan...